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How to get rid of ulcers? Treating ulcers involves a multifaceted approach that may include medication, lifestyle changes, and dietary adjustments. Depending on the type of ulcer, doctors may prescribe antibiotics to treat infections or proton pump inhibitors (PPIs) to reduce stomach acid production and promote healing. Lifestyle changes such as quitting smoking, managing stress, and avoiding alcohol and nonsteroidal anti-inflammatory drugs (NSAIDs) can also help. Additionally, adopting a diet rich in fruits, vegetables, whole grains, and lean proteins while limiting spicy foods, caffeine, and acidic foods can aid in ulcer management by reducing irritation to the stomach lining.